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The classical Wald statistic which is used for constructing confidence intervals for proportions produces too narrow a confidence interval when the difference in proportions is close to zero or one (Newcombe (1998)). Newcombe, instead, suggests using a modification of Wilson's (1927) method based on a single proportion. Agresti & Kin (2005) also find Wilson's method produces good coverage and also suggest an improved confidence interval may be obtained by a simple modification of the Wald statistic. These are all included in this EXCEL [attachment:paired_pci.xls: spreadsheet.] The classical Wald statistic which is used for constructing confidence intervals for proportions produces too narrow a confidence interval when the difference in proportions is close to zero or one (Newcombe (1998)). Newcombe, instead, suggests using a modification of Wilson's (1927) method based on a single proportion. Agresti & Kin (2005) also find Wilson's method produces good coverage and also suggest an improved confidence interval may be obtained by a simple modification of the Wald statistic. These are all included in this EXCEL [attachment:paired_pci.xls  spreadsheet.]

Confidence interval for paired binomial proportions

The classical Wald statistic which is used for constructing confidence intervals for proportions produces too narrow a confidence interval when the difference in proportions is close to zero or one (Newcombe (1998)). Newcombe, instead, suggests using a modification of Wilson's (1927) method based on a single proportion. Agresti & Kin (2005) also find Wilson's method produces good coverage and also suggest an improved confidence interval may be obtained by a simple modification of the Wald statistic. These are all included in this EXCEL [attachment:paired_pci.xls spreadsheet.]

References

[attachment:agresti.pdf Agresti A and Min Y (2005) Simple improved confidence intervals for comparing matched proportions.] Statistics in Medicine 24(5) 729-740.

Newcombe RG (1998) Improved confidence intervals for the difference between binomial proportions based on paired data. Statistics in Medicine 17 2635-2650.

Lee S & Lee S-C (2007) An improved confidence interval for the population proportion in a double sampling scheme subject to false-positive misclassification, Journal of the Korean Statistical Society 36 275–284. (reference for agrestic-oull method used in above spreadsheet).

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